As a result, irrigation became a substantial national issue.

Although the show might sound genteel, it is full of substantial issues.

"You have substantial literary issues at stake here," one participant said.

Involvement of religious organizations in politics raises a substantial legal issue.

Increasingly, even traditional women's magazines are focusing on substantial issues.

Several substantial issues, including how to spend a proposed $1.9 billion environmental bond issue, remain unresolved.

There is another equally substantial issue, moreover, of judicial cooperation.

One of these substantial issues is the relationship between the courts.

I agree that this is a substantial and important issue.

Some meetings involved substantial issues, like the conflict in the Balkans or trade.