In particular, we believe that a deal must be structured to provide substantial relief for these homeowners.

With treatment, many feel substantial relief in 4-6 weeks.

"It is encouraging," she said, "but we are looking for substantial relief."

The proposal would have them wait six years for substantial relief.

Baghdad's numerous other creditors should also grant substantial relief.

Most doctors believe that the benefits of daily use outweigh the risks for those who get substantial relief.

"We were all able to recognize it as a package that at least offers some substantial relief, if it does include more taxes."

Nine of the 11 reported substantial relief of their symptoms within a week, while none in the comparison group got better.

"Together, we believe these changes can produce substantial new relief for the poorest countries," he said.

The majority reported complete or substantial relief from menopausal symptoms, and 85 percent preferred the lower dose.