VDRL is the only test where the result of a confirmed syphilis infection can become negative after successful treatment.

Remember, a syphilis infection manifests itself in many different ways.

Pregnancy does not appear to alter the clinical course, manifestations, or diagnostic test results of syphilis infection among adults.

Patients who might be carrying the syphilis infection were thus released, spreading the disease.

In the developed world, syphilis infections were in decline until the 1980s and 1990s due to widespread use of antibiotics.

If taken properly, antibiotic treatment with penicillin will usually cure a syphilis infection.

In rare cases, the first attempt at treatment does not cure the syphilis infection.

The tests are used to screen for or to confirm a syphilis infection.

It is more difficult to do and may be used to confirm a syphilis infection after another method tests positive for the syphilis bacteria.

It is used as a confirmatory test for syphilis infection.