Depigmentation of the skin can be caused by a number of local and systemic conditions.

Rarely the bite may also produce the systemic condition with occasional fatalities.

As such, intermediate uveitis may be the first expression of a systemic condition.

About 30-40% have an underlying systemic autoimmune condition.

Reis-Bucklers corneal dystrophy is not associated with any systemic conditions.

There are certain systemic conditions that can be found in the eyes as well, diabetes, high blood pressure, high cholesterol.

The majority of service users were elderly individuals who often had disabilities due to systemic medical conditions.

Medical care is directed at treating systemic conditions and improving the person's quality of life.

Correlating oral status with systemic condition of the patient is thus critically important.

Patients over 65 years suffering from a severe systemic condition were considered as high risk cases.