Take off in the first direction that appeals to you?
Julian nodded and took off in the direction of the kitchen.
The dog took off in the direction he'd come from.
As one, they spun and took off in the other direction.
Then she took off in the direction of Teresa's room while the police made the necessary phone calls.
I may have taken off in the wrong direction entirely.
I took off in the other direction, making enough noise to draw their attention.
They'll probably be scared to hell if they hear you, take off in the opposite direction.
Wild Tony took off in the direction of his men at a run.
A car or two, the wrong ones, took off down the street in the direction of the town.