This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes.
They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development.
Our study concurs with such observations, since we show that ERβ expression is associated with terminal differentiation of trophoblast.
Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis.
In neural precursor cells, high levels of geminin prevent terminal differentiation.
Erythropoietin, a growth factor, is added, coaxing the stem cells to complete terminal differentiation into red blood cells.
Chondrocytes undergo terminal differentiation when they become hypertrophic during endochondral ossification.
Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation.
The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells.
Following terminal differentiation in vivo, mature oligodendrocytes wrap around and myelinate axons.