Reducing the dose of therapeutic antibodies to limit the extent of trogocytosis might improve their therapeutic efficay.

Consequently, diabody drugs could be dosed much lower than other therapeutic antibodies and are capable of highly specific targeting of tumors in vivo.

Immunohistochemistry is used to determine patients who may benefit from therapeutic antibodies such as Erbitux (cetuximab).

Examples of biological therapy include anti-cancer immunotherapy (using therapeutic monoclonal antibodies, growth factors or vaccines) and gene therapy.

Stratacyte has begun development of two therapeutic monoclonal antibodies.

Initial therapeutic antibodies were simple murine analogues, which contributed to the early lack of success.

Recently, the bispecific antibodies, a novel class of therapeutic antibodies, have yielded promising results in clinical trials.

In 2007, eight of the 20 best-selling biotechnology drugs in the U.S. are therapeutic monoclonal antibodies.

This technology is widely exploited in pharmaceutical industry for the discovery and development of therapeutic monoclonal antibodies to treat mainly cancer, inflammatory and infectious diseases.

His research interests during this period included the regulation of the immune response and the generation of therapeutic antibodies.