CAT is used as a reporter system to measure the level of a promoter or its tissue-specific expression.
We reasoned that some genes might exhibit highly tissue-specific expression, such that most of the ESTs comprising a transcript would be derived from the tissue.
Further research was started to analyse tissue-specific expression of several transcripts.
In addition to the genes whose tissue-specific expression was confirmed by this array analysis, many have not been characterized previously.
Developmental and tissue-specific expression of the Q5k gene.
C-type lamins are also subject to tissue-specific expression.
Sonkoly et al. found that miR-203 displays a highly organ- and tissue-specific expression across 21 human organs and tissues analyzed.
The highest level of transgene expression occurs in the brain, indicating that the regulatory sequences that direct tissue-specific expression are present on this fragment (Figure 4).
However, in the majority of cases the LTR functions as one of many alternate promoters, often conferring tissue-specific expression related to reproduction and development.
The PLP autoantigen is expressed in alternatively spliced forms, which exhibit tissue-specific expression.