The town was almost destroyed by a great fire in 1688.

In 1827 the town and the university were destroyed by fire.

In 1925, the entire town was destroyed by a fire.

In 1610, almost half the town was destroyed by fire.

A large fire destroyed almost the whole town in 1496.

In 1797, a large fire destroyed almost the entire town.

On 18 March 1560 the town was destroyed by fire.

During a civil war in 1883, the town was destroyed.

About 80% of the town was destroyed, including one hospital.

The town was destroyed by a fire in 1794, but it could not stop the town's development.