Within days, they observed that the "treated mice formed insulin producing cells that acted like bona fide beta cells."
Dr. Auwerx attributes this in large part to the significantly increased number of mitochondria he detected in the muscle cells of treated mice.
The treated mice were alive.
Encephalitogenic T cells recovered from treated mice were hypo-responsive to myelin antigen and failed to adoptively transfer the disease.
The shivering abated in more than half the treated mice, and some seemed fully normal.
Behavioral tests and learning scores of the treated mice showed rapid improvement after treatment, providing results that rivaled non-treated mice.
The 'controls' were looking very sick, but the two treated mice seemed very well.
In fact, the median survival time of treated mice was 51 days as opposed to 32 days for the controls.
Physical activity among the treated mice was much greater than in the control group.
At the same time, these dexamethsone treated mice were resistant to inflammatory stimulus.