Most are familiar, but they may be used in unfamiliar ways.

The sound struck my ear in a most unfamiliar way.

The word "perspective" is being used here in an unfamiliar way.

In other words, a student learns to use the mind in ways unfamiliar to us.

But she was relieved that she didn't have to give up her freedom yet, for the company of people with unfamiliar ways.

After only a few years he left the suburb and its unfamiliar way of life.

He feared me in both a familiar and unfamiliar way.

The clothes felt uncomfortable and touched him in unfamiliar ways, but those were minor details.

He looked disturbed, but not afraid; excited, rather, in an unfamiliar way.

It is a pleasant if unfamiliar way to define himself.