In fact, nearly everyone at one time has had an unpleasant reaction to something they ate.
While frowns that involve movement of the cheeks reflect an unpleasant reaction.
Like disulfiram, it can produce an unpleasant reaction when consumed with alcohol.
Thus, after a month of truly unpleasant reaction and growth, he found himself a physical twenty-year-old with a sixty-year-old's mind.
For years he could not tolerate the sight of May bugs without a return of this unpleasant reaction.
A brief encounter by the two some time later results in an unpleasant reaction by Frankie.
It turned out I was having an unexpected and thoroughly unpleasant respiratory reaction to the candles scattered throughout my apartment.
Side effects are predictable but often unpleasant reactions to a drug.
Perhaps many people aren't "using it long enough" because they've had similarly unpleasant reactions.
Some people have unpleasant reactions to certain artificially colored foods.