If someone with all the right moves materialized, you would lose big.

It would have been divided in half and he'd have lost really big.

Not long ago, she played the slots and lost big.

They could lose big if these stocks move too far in the wrong direction.

While these ventures can lose big, at times they pay handsomely.

Saddam Hussein could lose big and still be a hero in some parts of the region.

And she would lose big, just as Janet had predicted.

On the other hand, the winner could just lose big.

But put a lot of money in a neighborhood bank and you could lose big.

I can't see any team playing to lose big just so they get the first pick in the draft!