This was a huge, nasty case no matter what.

Let him have a breath mask, and a nasty case of the bends for just punishment.

At first, it just seemed like a nasty case of the flu.

I've got a real nasty case that I'm working on.

Actually, I have a couple of nasty cases for you to work on.

And he had a nasty case waiting on the table for him.

But a nasty case of shingles put me literally on my back.

It was, some say, a nasty case of political poisoning.

A much smaller number of casualties, the really nasty cases, will be our direct responsibility.

Attorneys are busy, and sometimes they put it aside if it's not a big, nasty case.