The region gp120 of HIV-1 Env which contacts CD4, its primary receptor, is functionally conserved and vulnerable to neutralizing antibodies such as monoclonal antibody b12.

The 5-HT 2A receptor is the primary serotonergic receptor which couples to activation the ERK pathway in vascular smooth muscle cells [ 28 ] .

Specifically, a deficit in metabotropic glutamate receptors 1 and 5 (the primary post-synaptic receptors) results in a relative excess of the activity of the other 6 presynaptic receptors.

The first functions as a primary receptor, while the latter two have a co-receptor activity and enable AAV to enter the cell by receptor-mediated endocytosis.

HSPG functions as the primary receptor, though its abundance in the extracellular matrix can scavenge AAV particles and impair the infection efficiency.

The inner hair cells are the primary sensory receptors and a significant amount of the sensory input to the auditory cortex occurs from these hair cells.

It is the primary receptor for fibronectin.

CD4 is the primary receptor for HIV-1.

During his Ph.D. work, he discovered a link between acetylcholine and memory mechanisms by showing that acetylcholine modulates the primary receptor linked to synaptic plasticity.

Glucocorticoids could mediate the gene expression of ANP and its primary receptor, natriuretic peptide receptor A (NPR-A).