Absorbed parathion is rapidly metabolized to paraoxon, as described above.

Heroin is rapidly metabolized by esterase enzymes in the brain and has an extremely short half-life.

However, serotonin has a relatively short half-life since it is rapidly metabolized by monoamine oxidase.

An ester-linked local anesthetic agent, 2-chloroprocaine, is rapidly metabolized, and placental transfer is limited.

Fatty acids are rapidly metabolized.

When taken orally, though, it is rapidly metabolized.

Clevidipine is rapidly metabolized by esterases in the blood and extravascular tissues.

Clevidipine will still be rapidly metabolized in pseudocholinesterase-deficient patients.

Once ingested, psilocybin is rapidly metabolized to psilocin, which then acts on serotonin receptors in the brain.

It is rapidly metabolized into desacetylmetipranolol.