Biochemistry and replication machinery were not altered.
Suppose we want to suggest, for instance, that life began when both DNA and its protein-based replication machinery spontaneously chanced to come into existence.
The fact that the damage detection and repair systems are as complex as the replication machinery itself highlights the importance evolution has attached to DNA fidelity.
The virus exists as a naked circular piece of DNA called an episome and uses the cellular replication machinery to replicate itself.
The SV40 system proved to be a particularly useful system because SV40 relies largely on the cellular replication machinery for the duplication of its genome.
Not only for himself, but for the replication machinery as well.
One moment, he was in the empty cavern that had once housed the huge replication machinery.
It is unclear if any of the Phycodnaviruses encode a fully functional replication machinery, however.
Adenoviruses possess a linear dsDNA genome and are able to replicate in the nucleus of mammalian cells using the host's replication machinery.
Once the early genes have liberated adequate virus proteins, replication machinery, and replication substrates, replication of the adenovirus genome can occur.